Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF3 (PDZK1) Antibody

Primary Antibodies

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

PDZK1 Antibody is a Rabbit Polyclonal antibody against PDZK1. This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

PDZK1

Purified by affinity chromatography.