CARHSP1, 1-147aa, Human, His tag, E.coli

CRAHSP1 is a serine phosphoprotein originally identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B). This protein interacts with the STYX/dead phosphate protein in developing spermatids and is a paralog of the brain-specific mRNA-binding protein PIPPIN. It is thought to play a common role in calcium-mediated signal transduction resulting from phosphorylation on serine residues. Recombinant human CRAHSP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques

Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

0.5 mg/ml (determined by BCA)

• Schäfer C., et al. (2003) Am J Physiol Gastrointest Liver Physiol.. 285:G726-34
• Groblewski G.E, et al. (1998) J. Biol. Chem. 273: 22738-22744.

>, 90% by SDS - PAGE

MGSSHHHHHH SSGLVPRGSH MSSEPPPPPQ PPTHQASVGL LDTPRSRERS PSPLRGNVVP SPLPTRRTRT FSATVRASQG PVYKGVCKCF CRSKGHGFIT PADGGPDIFL HISDVEGEYV PVEGDEVTYK MCSIPPKNEK LQAVEVVITH LAPGTKHETW SGHVISS