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PSMA7, 1-248aa, Human, His-tagged, Recombinant, E.coli

ArtNr ARP-01-2011-0.5
Hersteller American Research Products
Menge 0.5 mg
Quantity options 0.5 mg 100 ug 20 ug
Kategorie
Typ Proteins Recombinant
Specific against other
Purity > 90% by SDS - PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MSYDRAITVF SPDGHLFQVE YAQEAVKKGS TAVGVRGRDI VVLGVEKKSV AKLQDERTVR KICALDDNVC MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE FLEKNYTDEA IETDDLTIKL VIKALLEVVQ SGGKNIELAV MR
Citations Cho S., et al. (2001) FEBS Lett. 498(1):62-6.Dong J,, et al. (2004) J Biol Chem. 279(20):21334-42.
NCBI NP_002783
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias C6, HSPC, MGC3755, RC6-1, XAPC7, Proteasome alpha 7 subunit, PSMA7 , Proteasome alpha 7 subunit Proteasome (prosome macropain) subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, PSMA 7, RC6 1, Proteasome subunit RC6 1, Proteasome subunit XAPC7.
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Description
Proteasome alpha 7, PSMA7, is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. PSMA7, belonged to the peptidase T1A family, is a 20S core alpha subunit of proteasome. This protein was found to interact specifically with two subdomains of HIF-1alpha and inhibited the transactivation function of HIF-1alpha under both normoxic and hypoxia-mimicking conditions. Recombinant PSMA7 protein was expressed in E.coli and purified by using conventional chromatography techniques.
Form
Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl
Storage
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms
C6, HSPC, MGC3755, RC6-1, XAPC7, Proteasome alpha 7 subunit, PSMA7 , Proteasome alpha 7 subunit Proteasome (prosome macropain) subunit alpha type 7, Proteasome alpha 7 subunit, Proteasome subunit alpha 4, Proteasome subunit alpha type 7, PSMA 7, RC6 1, Proteasome subunit RC6 1, Proteasome subunit XAPC7.
Concentration
1 mg/ml (determined by Bradford assay)
NCBI
NP_002783
References
  • Cho S., et al. (2001) FEBS Lett. 498(1):62-6.
  • Dong J, , et al. (2004) J Biol Chem. 279(20):21334-42.
Antigen Recognized in Species
Human
Purity
>, 90% by SDS - PAGE
Molecular Weight
30.0 kDa (268 aa), confirmed by MALDI-TOF.
Amino Acid Sequence
MGSSHHHHHH SSGLVPRGSH MSYDRAITVF SPDGHLFQVE YAQEAVKKGS TAVGVRGRDI VVLGVEKKSV AKLQDERTVR KICALDDNVC MAFAGLTADA RIVINRARVE CQSHRLTVED PVTVEYITRY IASLKQRYTQ SNGRRPFGIS ALIVGFDFDG TPRLYQTDPS GTYHAWKANA IGRGAKSVRE FLEKNYTDEA IETDDLTIKL VIKALLEVVQ SGGKNIELAV MRRDQSLKIL NPEEIEKYVA EIEKEKEENE KKKQKKAS
Gene Category
Enzymes

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.5 mg
Lieferbar: In stock
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