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HSP47(Colligin), 18-418aa, Human, His-Tagged, Recombinant, E.coli

HSP47(Colligin), 18-418aa, Human, His-Tagged, Recombinant, E.coli

ArtNr	ARP-01-2046-20
Hersteller	American Research Products
Menge	20 ug
Quantity options	0.5 mg 100 ug 20 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Purity	> 90% by SDS - PAGE
Sequence	MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAA EVKKPAAAAA PGTAEKLSPK AATLAERSAG LAFSLYQAMA KDQAVENILV SPVVVASSLG LVSLGGKATT ASQAKAVLSA EQLRDEEVHA GLGELLRSLS NSTARNVTWK LGSRLYGPSS VSFADDFVRS SKQHYNCEHS KINFRDKRSA LQSINEWAAQ TTDGKLPEVT KDVERTDGAL LVNAMFFKPH WD
Citations	Mohammed Tasab., et al. (2000) The EMBO Journal. 19(10): 2204-2211Maloney A., et al. (2007) Cancer Res. 67(7):3239-53
NCBI	NP_001226
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Collagen-binding protein, Serpin H1, SERPINH1, RA-A47, AsTP3, Heme oxygenase 1, HSP47, Collogin, 47 kDa heat shock protein, 47 kDa heat shock protein precursor, Arsenic transactivated protein 3, AsTP 3, CBP 1, CBP 2, CBP1, CBP2, Collagen binding protein, SERPINH2, Collagen binding protein 1, Collagen binding protein 2, Colligen, Colligin 1, Colligin 2, gp46, Heat shock protein 47, HGNC 1547, Hsp 47, J6, PIG 14, PIG14, PPROM, Proliferation inducing gene 14, Proliferation inducing gene 14 protein, RA A47, Rheumatoid arthritis antigen A 47, Rheumatoid arthritis related antigen RA A47, Serine or cysteine proteinase inhibitor clade H member 1, Serine or cysteine proteinase inhibitor clade H member 2, Serpin H1, Serpin peptidase inhibitor clade H member 1.
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Description	Description: Heat shock protein 47(HSP47), also known as Colligin or Serpin H1, is a serpin which serves as a human chaperone protein for collagen. This protein is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein acts as a molecular chaperone facilitating the folding and assembly of procollagen molecules, retaining unfolded molecules within the ER, and assisting the transport of correctly folded-molecules from the ER to Golgi apparatus. Recombinant human HSP47/Colligin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Form	Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	Collagen-binding protein, Serpin H1, SERPINH1, RA-A47, AsTP3, Heme oxygenase 1, HSP47, Collogin, 47 kDa heat shock protein, 47 kDa heat shock protein precursor, Arsenic transactivated protein 3, AsTP 3, CBP 1, CBP 2, CBP1, CBP2, Collagen binding protein, SERPINH2, Collagen binding protein 1, Collagen binding protein 2, Colligen, Colligin 1, Colligin 2, gp46, Heat shock protein 47, HGNC 1547, Hsp 47, J6, PIG 14, PIG14, PPROM, Proliferation inducing gene 14, Proliferation inducing gene 14 protein, RA A47, Rheumatoid arthritis antigen A 47, Rheumatoid arthritis related antigen RA A47, Serine or cysteine proteinase inhibitor clade H member 1, Serine or cysteine proteinase inhibitor clade H member 2, Serpin H1, Serpin peptidase inhibitor clade H member 1.
Concentration	1 mg/ml (determined by Bradford assay)
NCBI	NP_001226
References	Mohammed Tasab., et al. (2000) The EMBO Journal. 19(10): 2204-2211 Maloney A., et al. (2007) Cancer Res. 67(7):3239-53
Antigen Recognized in Species	Human
Purity	>, 90% by SDS - PAGE
Molecular Weight	48.9 kDa (439 aa), confirmed by MALDI-TOF.
Amino Acid Sequence	MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAA EVKKPAAAAA PGTAEKLSPK AATLAERSAG LAFSLYQAMA KDQAVENILV SPVVVASSLG LVSLGGKATT ASQAKAVLSA EQLRDEEVHA GLGELLRSLS NSTARNVTWK LGSRLYGPSS VSFADDFVRS SKQHYNCEHS KINFRDKRSA LQSINEWAAQ TTDGKLPEVT KDVERTDGAL LVNAMFFKPH WDEKFHHKMV DNRGFMVTRS YTVGVMMMHR TGLYNYYDDE KEKLQIVEMP LAHKLSSLII LMPHHVEPLE RLEKLLTKEQ LKIWMGKMQK KAVAISLPKG VVEVTHDLQK HLAGLGLTEA IDKNKADLSR MSGKKDLYLA SVFHATAFEL DTDGNPFDQD IYGREELRSP KLFYADHPFI FLVRDTQSGS LLFIGRLVRP KGDKMRDEL
Gene Category	Heat Shock Proteins

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Menge: 20 ug

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