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Alpha-enolase, 1-434aa, Human, E.coli

Alpha-enolase, 1-434aa, Human, E.coli

ArtNr	ARP-01-2179-100
Hersteller	American Research Products
Menge	100 ug
Quantity options	0.5 mg 100 ug 20 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Purity	> 90% by SDS - PAGE
Sequence	MSILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK AGAVEKGVPL YRHIADLAGN SEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAANFRE AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEGLELLKTA IG
Citations	Das R., et al. (2009) Blood. 113(22):5371-2.Ueno NT., et al. (2008) Cancer Res. 68(22):9302-10.
NCBI	NP_001419
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Non-Neuronal Enolase (NNE), Enolase-1, ENO1, MBP-1, MYC promoter-binding protein 1, PPH, tau-crystallin, 2 phospho D glycerate hydro lyase, Alpha enolase, C myc promoter binding protein, EC 4.2.1.11, ENO1L1, Enolase 1, Enolase 1 (alpha), Enolase 1 (alpha) like 1, MBP 1, MBP1, MBPB1, MPB 1, MPB1, PPH, MYC promoter binding protein 1, NNE, Non neural enolase, Phosphopyruvate hydratase, Plasminogen binding protein,
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Description	Alpha-enolase, also known as Enolase 1, is one of three enolase isoenzymes and a glycolytic enzyme expressed in most tissues. This protein plays a key role in anaerobic metabolism under hypoxic conditions and may act as a cell surface plasminogen receptor during tissue invasion. Abnormal expression of alpha-enolase is associated with tumor progression in some cases of breast and lung cancer. It also has been identified as an autoantigen associated with Hashimoto's encephalopathy and severe asthma. Recombinant human alpha-enolase was expressed in E.coli and purified by using conventional chromatography.
Form	Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 1 mM MgSO4, 10% Glycerol
Storage	Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms	Non-Neuronal Enolase (NNE), Enolase-1, ENO1, MBP-1, MYC promoter-binding protein 1, PPH, tau-crystallin, 2 phospho D glycerate hydro lyase, Alpha enolase, C myc promoter binding protein, EC 4.2.1.11, ENO1L1, Enolase 1, Enolase 1 (alpha), Enolase 1 (alpha) like 1, MBP 1, MBP1, MBPB1, MPB 1, MPB1, PPH, MYC promoter binding protein 1, NNE, Non neural enolase, Phosphopyruvate hydratase, Plasminogen binding protein,
Concentration	1 mg/ml (determined by Bradford assay)
NCBI	NP_001419
References	Das R., et al. (2009) Blood. 113(22):5371-2. Ueno NT., et al. (2008) Cancer Res. 68(22):9302-10.
Antigen Recognized in Species	Human
Purity	>, 90% by SDS - PAGE
Molecular Weight	47.1 kDa (434aa), confirmed by MALDI-TOF.
Amino Acid Sequence	MSILKIHARE IFDSRGNPTV EVDLFTSKGL FRAAVPSGAS TGIYEALELR DNDKTRYMGK GVSKAVEHIN KTIAPALVSK KLNVTEQEKI DKLMIEMDGT ENKSKFGANA ILGVSLAVCK AGAVEKGVPL YRHIADLAGN SEVILPVPAF NVINGGSHAG NKLAMQEFMI LPVGAANFRE AMRIGAEVYH NLKNVIKEKY GKDATNVGDE GGFAPNILEN KEGLELLKTA IGKAGYTDKV VIGMDVAASE FFRSGKYDLD FKSPDDPSRY ISPDQLADLY KSFIKDYPVV SIEDPFDQDD WGAWQKFTAS AGIQVVGDDL TVTNPKRIAK AVNEKSCNCL LLKVNQIGSV TESLQACKLA QANGWGVMVS HRSGETEDTF IADLVVGLCT GQIKTGAPCR SERLAKYNQL LRIEEELGSK AKFAGRNFRN PLAK
Gene Category	Metabolism

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