Fibroblast Growth Factor-acidic, FGF-acidic, Rat, Recombinant

FGF-acidic is one of 23 known members of the FGF family. nbsp, Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. nbsp, FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. nbsp, FGF-acidic has the ability to signal through all the FGF receptors. nbsp, Recombinant rat FGF-acidic is a 15.9 kDa protein consisting of 141 amino acid residues.

FGF-1, HBGF-1, ECGF-beta

E. Coli

MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D

Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED 50 is a‰¤ 0.1 ng/ml, in the presence of 10 ug/ml heparin, corresponding to a specific activity of a‰¥ 1 x 10^7 units/mg.

Verified by N-terminal and Mass Spectrometry analyses (when applicable).