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Anti-MALT1 Antibody

ArtNr ABC-ABO11223
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen WB
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MALT1, MLT, MALT lymphoma-associated translocation, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase, 3.4.22.-
Lieferbar
Primary Accession
Q9UDY8
Application
WB
Clonality
Polyclonal
Gene ID
10892
Reactivity
H
Legend image 1
Anti-MALT1 antibody, ABO11223, Western blottingLane 1: MCF-7 Cell LysateLane 2: HELA Cell Lysate
Type image 1
WB
Dilution image 1
0.1-0.5 µg/ml
Calculated MW
92272
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Description
Rabbit IgG polyclonal antibody for Mucosa-associated lymphoid tissue lymphoma translocation protein 1(MALT1) detection. Tested with WB in Human.
Protein Function
Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion. .
Subcellular Localization
Cytoplasm, perinuclear region . Nucleus . Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.
Tissue Specificity
Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung.
Protein Name
Mucosa-associated lymphoid tissue lymphoma translocation protein 1
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MALT1(809-824aa DEIPFSFSDRLRISEK).
Purification
Immunogen affinity purified.
Cross Reactivity
No cross reactivity with other proteins
Storage
At -20?C for one year. After r?Constitution, at 4?C for one month. It?Can also be aliquotted and stored frozen at -20?C for a longer time.Avoid repeated freezing and thawing.
Concentration (mg/ml)
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Sequence Similarities
Belongs to the peptidase C14B family.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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