Vergleich

Goat Anti-Choline acetyltransferase Antibody

ArtNr ABC-AF1238a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA
Specific against other
Host Goat
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products ChAT, CHAT, Choline O-acetyltransferase, CHOACTase, Choline acetylase, 2.3.1.6
Lieferbar
Primary Accession
P28329
Antigen Type
Synthetic Peptide
Application
WB, E
Bio Background
This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.
Bio References
Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.
Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? Rua帽o G, et al. Pharmacogenomics, 2010 Jul. PMID 20602615.
Redesign of cosubstrate specificity and identification of important residues for substrate binding to hChAT. Green KD, et al. Biochemistry, 2010 Jul 27. PMID 20560540.
Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes. Sloan CD, et al. Am J Med Genet B Neuropsychiatr Genet, 2010 Jul. PMID 20468060.
Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers. Wei J, et al. Hum Genet, 2010 Jun. PMID 20383528.
Clonality
Polyclonal
Gene ID
1103
Gene Name
CHAT
Subtitle
Peptide-affinity purified goat antibody
Reactivity
H
Legend image 1
AF1238a (0.03 µg/ml) staining of Human Placenta lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Type image 1
WB
Other Accession
NP_001136405; 1103;
Predicted
Pig, Dog, Cow
Concentration (mg/ml)
100ug/200ul

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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