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SILV Antibody (Center)

SILV Antibody (Center)

ArtNr	ABC-AP13753c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	SILV, PMEL, D12S53E, PMEL17, Melanocyte protein PMEL, ME20-M, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, P1, P100, Premelanosome protein, Silver locus protein homolog, M-alpha, P26, ME20M, 95 kDa melanocyte-specific secreted glycoprotein, Secreted melanoma-associated ME20 antigen, ME20-S, ME20S, M-beta
Lieferbar
Primary Accession	P40967
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Bio References	Leonhardt, R.M., et al. J. Biol. Chem. 285(21):16166-16183(2010) Hoashi, T., et al. FASEB J. 24(3):916-930(2010) Watt, B., et al. J. Biol. Chem. 284(51):35543-35555(2009) McGlinchey, R.P., et al. Proc. Natl. Acad. Sci. U.S.A. 106(33):13731-13736(2009) Kummer, M.P., et al. J. Biol. Chem. 284(4):2296-2306(2009)
Clonality	Polyclonal
Clone/Animal Names	RB33755
Gene ID	6490
Gene Name	PMEL
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	SILV Antibody (Center) (Cat. #AP13753c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SILV antibody detected the SILV protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_008859.1
Isotype	Rabbit Ig
Calculated MW	70255
Antigen Region	412-440
Antigen Source	HUMAN
Target/Specificity	This SILV antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 412-440 amino acids from the Central region of human SILV.
NCBI Accession	NP_001186982.1; NP_001186983.1; NP_008859.1

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ABC-AP13753c-ev-datasheet.pdf

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Menge: 80 ul

lieferbar

Lieferung vsl. bis 04.09.2025