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HTATIP2 Antibody (N-term)

HTATIP2 Antibody (N-term)

ArtNr	ABC-AP14762a-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Oxidoreductase HTATIP2, 30 kDa HIV-1 TAT-interacting protein, HIV-1 TAT-interactive protein 2, 111-, HTATIP2 (HGNC:16637)
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Primary Accession	Q9BUP3
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	Oxidoreductase required for tumor suppression. NAPDH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import. Isoform 1 is a metastasis suppressor with proapoptotic as well as antiangiogenic properties. Isoform 2 has an antiapoptotic effect.
Bio References	Chen, X., et al. Dig. Dis. Sci. 55(8):2219-2226(2010) Fong, S., et al. BMC Cell Biol. 11, 23 (2010) : Nakahara, J., et al. Expert Opin. Ther. Targets 13(12):1375-1386(2009) Tong, X., et al. Am. J. Pathol. 174(5):1931-1939(2009) Nakahara, J., et al. J. Clin. Invest. 119(1):169-181(2009)
Clonality	Polyclonal
Clone/Animal Names	RB35013
Gene ID	10553
Gene Name	HTATIP2 (HGNC:16637)
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	HTATIP2 Antibody (N-term) (Cat. #AP14762a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HTATIP2 antibody detected the HTATIP2 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	HTATIP2 Antibody (N-term) (AP14762a)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of HTATIP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q9Z2G9; NP_001091991.1; NP_001091993.1; NP_001091992.1
Predicted	M
Isotype	Rabbit Ig
Calculated MW	27049
Antigen Region	45-74
Antigen Source	HUMAN
Target/Specificity	This HTATIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-74 amino acids from the N-terminal region of human HTATIP2.
NCBI Accession	NP_001091990.1; NP_001091991.1; NP_001091992.1; NP_001091993.1; NP_006401.3

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