BF Antibody (Center)

ArtNr	ABC-AP7357c-ev
Hersteller	Abcepta
Menge	80 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CFB, C3/C5 convertase, BF, BFD, GBG, PBF2, Complement factor B Bb fragment, Glycine-rich beta glycoprotein, Properdin factor B, Complement factor B, Complement factor B Ba fragment
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Primary Accession	P00751
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	BF is complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation.
Bio References	Baatz, H., Klin Monatsbl Augenheilkd 226 (8), 654-658 (2009) Goring, K., Am. J. Physiol., Cell Physiol. 296 (5), C1140-C1150 (2009)
Clonality	Polyclonal
Clone/Animal Names	RB18685
Gene ID	629
Gene Name	CFB
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of BF Antibody (Center) (Cat.# AP7357c) in HepG2 cell line and mouse liver tissue lysates (35ug/lane). BF (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	BF Antibody (Center) (RB18685) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BF Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:50~100
Isotype	Rabbit Ig
Calculated MW	85533
Antigen Region	395-422
Antigen Source	HUMAN
Target/Specificity	This BF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the Central region of human BF.
NCBI Accession	NP_001701.2

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Menge: 80 ul

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