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NAB2 Antibody (Center)

NAB2 Antibody (Center)

ArtNr	ABC-AP7635c
Hersteller	Abcepta
Menge	400 ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applikationen	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	NAB2, MADER, EGR-1-binding protein 2, Melanoma-associated delayed early response protein, NGFI-A-binding protein 2, Protein MADER
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Primary Accession	Q15742
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	NAB2 is a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by this protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex.
Bio References	Srinivasan, R., J. Biol. Chem. 281 (22), 15129-15137 (2006) Kumbrink, J., J. Biol. Chem. 280 (52), 42785-42793 (2005) Lucerna, M., J. Biol. Chem. 278 (13), 11433-11440 (2003)
Clonality	Polyclonal
Clone/Animal Names	RB18506
Gene ID	4665
Gene Name	NAB2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	Western blot analysis of NAB2 antibody (Center) (Cat.#AP7635c) in A375 cell line lysates (35ug/lane). NAB2 (arrow) was detected using the purified Pab.
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q61127
Predicted	M
Isotype	Rabbit Ig
Calculated MW	56594
Antigen Region	109-138
Antigen Source	HUMAN
Target/Specificity	This NAB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-138 amino acids from the Central region of human NAB2.
NCBI Accession	NP_005958.1

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Menge: 400 ul

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