Vergleich

TLX1 Antibody

ArtNr ABC-ASC11661
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Applikationen WB, ELISA, IHC-P
Specific against other
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Primary Accession
P31314
Application
WB, IHC-P, E
Bio Background
TLX1 Antibody: The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.
Bio References
Dear TN, Sanchez-Garcia I, and Rabbitts TH, et al. The Hox11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes. Proc. Natl. Acad. Sci. USA 1993; 90:4431-5.
Dube ID, Kamel-Reid S, Yuan CC, et al. A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t (10; 14). Blood 1991; 78:2996-3003.
Hatano M, Roberts CW, Minden M, et al. Deregulation of a homeobox gene, Hox11, by the t (10; 14) in T cell leukemia. Science 1991; 253:79-82.
Roberts CW, Shutter JR, Korsmeyer SJ et al. Hox11 controls the genesis of the spleen. Nature 1994; 368:747-9.
Clonality
Polyclonal
Gene ID
3195
Gene Name
TLX1
Reactivity
H, M, Rat
Legend image 1
Western blot analysis of TLX1 in mouse spleen tissue lysate with TLX1 antibody at (A) 1 µg/mL and (B) 2 µg/mL.
Type image 1
WB
Legend image 2
Immunohistochemistry of TLX1 in human spleen tissue with TLX1 antibody at 2.5 µg/ml.
Type image 2
IHC
Other Accession
NP_005512; 5031757
Isotype
IgG
Calculated MW
34365
Antigen Source
homo sapiens
Target/Specificity
TLX1; Multiple isoforms of TLX1 exist due to alternative splicing events. TLX1 antibody is predicted to not cross-react with other TLX proteins.
Purification
TLX1 Antibody is affinity chromatography purified via peptide column.
Reconstitution & Storage
TLX1 antibody can be stored at 4℃ for three months and -20℃, stable for up to one year.
Antibody Form
Liquid
Application Notes
TLX1 antibody can be used for detection of TLX1 by Western blot at 1 - 2 µg/mL.
Positive Control
Mouse Spleen Tissue Lysate;
Buffer
TLX1 Antibody is supplied in PBS containing 0.02% sodium azide.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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Lieferung vsl. bis 04.09.2025 

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