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BANF1 Antibody (monoclonal) (M07)

ArtNr ABC-AT1267a
Hersteller Abcepta
Menge 100 ug
Kategorie
Typ Antibody Primary
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Applikationen WB, IF, ELISA
Clon M2
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products BANF1, N-terminally processed, BAF, BCRG1, Barrier-to-autointegration factor, Breakpoint cluster region protein 1
Lieferbar
Primary Accession
O75531
Antigen Type
Recombinant Protein
Application
WB, IF, E
Bio Background
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Bio References
1.Functional Disruption of the Moloney Murine Leukemia Virus Preintegration Complex by Vaccinia-related Kinases.Suzuki Y, Ogawa K, Koyanagi Y, Suzuki Y.J Biol Chem. 2010 Jul 30; 285(31):24032-43. Epub 2010 May 28.
Clonality
Monoclonal
Gene ID
8815
Gene Name
BANF1
Subtitle
Mouse monoclonal antibody raised against a full length recombinant BANF1.
Reactivity
H, M, Rat
Legend image 1
Immunofluorescence of monoclonal antibody to BANF1 on HeLa cell. [antibody concentration 10 ug/ml]
Type image 1
IF
Legend image 2
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.53 KDa) .
Type image 2
WB
Dilution image 2
1:500~1000
Legend image 3
BANF1 monoclonal antibody (M07), clone M2. Western Blot analysis of BANF1 expression in PC-12.
Type image 3
WB
Dilution image 3
1:500~1000
Legend image 4
BANF1 monoclonal antibody (M07), clone M2. Western Blot analysis of BANF1 expression in Raw 264.7.
Type image 4
WB
Dilution image 4
1:500~1000
Legend image 5
BANF1 monoclonal antibody (M07), clone M2. Western Blot analysis of BANF1 expression in Jurkat.
Type image 5
WB
Dilution image 5
1:500~1000
Legend image 6
Detection limit for recombinant GST tagged BANF1 is approximately 10ng/ml as a capture antibody.
Type image 6
E
Other Accession
BC005942
Isotype
IgG2a Kappa
Antigen Source
Human: ~~ Positive
Target/Specificity
BANF1 (AAH05942, 1 a.a. ~ 89 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
NCBI Accession
NP_001137457.1; NP_003851.1
Clone: M2
Org Accession
AAH05942
Gene Description
barrier to autointegration factor 1
Gene Summary
The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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