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Stromal Interaction Molecule 1 (STIM1) Antibody Europäischer Partner

ArtNr abx005528-200
Hersteller Abbexa
Menge 2 x 100 ul
Quantity options 100 ul 20 ul 2 x 100 ul 50 ul
Kategorie
Typ Antibody Primary
Format Liquid
Applikationen WB, IF, IP, ICC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Lieferbar
Manufacturer - Category
Primary Antibodies
Manufacturer - Targets
Stromal Interaction Molecule 1 (STIM1)
Manufacturer - Conjugate / Tag
Unconjugated
Storage Conditions
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight
Calculated MW: 77 kDa
Observed MW: 85 kDa
Description
STIM1 Antibody is a Rabbit Polyclonal antibody against STIM1. This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region, as well as early hematopoiesis, by mediating attachment to stromal cells. Mutations in this gene are associated with fatal classic Kaposi sarcoma, immunodeficiency due to defects in store-operated calcium entry (SOCE) in fibroblasts, ectodermal dysplasia and tubular aggregate myopathy. This gene is oriented in a head-to-tail configuration with the ribonucleotide reductase 1 gene (RRM1), with the 3' end of this gene situated 1.6 kb from the 5' end of the RRM1 gene. Alternative splicing of this gene results in multiple transcript variants.
Dry Ice
No
Buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Clonality
Polyclonal
Note
This product is for research use only.
Purification
Purified by affinity chromatography.
UniProt Entry Name
STIM1_HUMAN

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 2 x 100 ul
Lieferbar: In stock
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