Ep-CAM / CD326(Cocktail PAN-EpCAM), CF488A conjugate, 0.1mg/mL

Primary

Antibodies

CF488A

Room temperature

40-43 kDa

This is a cocktail of four highly specific monoclonal antibodies (EGP40/826, EGP40/837, EGP40/1110, EGP40/1120) that recognize extracellular as well as intracellular domains of the epithelial cellular adhesion molecule (Ep-CAM). Epithelial specific antigen (ESA), or Ep-CAM, is a 40-43 kDa transmembrane epithelial glycoprotein expressed on the basolateral cell surface in most simple epithelia and a vast majority of carcinomas. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.

Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

2 years

41116161

0.05% sodium azide (CAS 26628-22-8)

PBS, 0.1% BSA, 0.05% azide

Recombinant human Ep-CAM protein (full-length and fragments)

For research use only (RUO)

542050

Exosomes/EVs|Plasma membrane

Adenocarcinoma

CD326|Ep-CAM