Lactoylglutathione Lyase(CPTC-GLO1-1), 0.2mg/mL

IHC, FFPE (verified)|WB (verified)

Lactoylglutathione Lyase

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Store at 2 to 8°C|Protect fluorescent conjugates from light

GLO1 is an enzyme involved in the detoxification of methylgyoxal, a byproduct of glycolysis. GLO1 expression has been demonstrated by several studies to be upregulated in various human malignant tumors, including metastatic melanoma and lung carcinoma, and thus is a target for pharmaceutical development. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Stable at room temperature or 37°C (98°F) for 7 days.

Primary and secondary antibodies for multiple methodology
immunostaining detection application

0.2 mg/mL

Guaranteed for at least 24 months from date of receipt when stored as recommended

Monoclonal

GLO1

A431, HepG2, MOLT and Raji cell lysates. Ovarian carcinoma or prostate carcinoma.

Lung cancer|Melanoma

Aldoketomutase, epididymis secretory protein Li 74, Glo1, Glx I, glyoxalase 1 complex, glyoxalase 1 regulatory, glyoxalase 1 structural, glyoxalase domain containing 1, Glyoxalase I, glyoxylase 1, Ketone-aldehyde mutase, lactoyl glutathione lyase, Lactoylglutathione lyase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase