ADAM10 Antibody

ArtNr	CSB-PA001273LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	IF, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	A disintegrin and metalloprotease domain 10 antibody; A disintegrin and metalloproteinase domain 10 antibody; AD 10 antibody; AD10 antibody; AD18 antibody; ADA10_HUMAN antibody; ADAM 10 antibody; ADAM metallopeptidase domain 10 antibody; ADAM10 antibody; CD 156c antibody; CD156c antibody; CD156c antigen antibody; CDw156 antibody; disintegrin and metalloproteinase domain containing protein 10 antibody; Disintegrin and metalloproteinase domain-containing protein 10 antibody; HsT 18717 antibody; HsT18717 antibody; Kuz antibody; Kuzbanian antibody; Kuzbanian protein homolog antibody; Kuzbanian; Drosophila; homolog of antibody; MADM antibody; Mammalian disintegrin metalloprotease antibody; Mammalian disintegrin-metalloprotease antibody; RAK antibody
Similar products	ADAM10, Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c), KUZ MADM
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	Intermediate capsid protein VP6
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	A disintegrin and metalloprotease domain 10 antibody; A disintegrin and metalloproteinase domain 10 antibody; AD 10 antibody; AD10 antibody; AD18 antibody; ADA10_HUMAN antibody; ADAM 10 antibody; ADAM metallopeptidase domain 10 antibody; ADAM10 antibody; CD 156c antibody; CD156c antibody; CD156c antigen antibody; CDw156 antibody; disintegrin and metalloproteinase domain containing protein 10 antibody; Disintegrin and metalloproteinase domain-containing protein 10 antibody; HsT 18717 antibody; HsT18717 antibody; Kuz antibody; Kuzbanian antibody; Kuzbanian protein homolog antibody; Kuzbanian; Drosophila; homolog of antibody; MADM antibody; Mammalian disintegrin metalloprotease antibody; Mammalian disintegrin-metalloprotease antibody; RAK antibody
Immunogen Species	Human
Immunogen	Recombinant Human Disintegrin and metalloproteinase domain-containing protein 10 protein (214-504AA)
Dilution	ELISA:1:2000-1:10000 IHC:1:20-1:200 IF:1:50-1:200
Background	Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-\|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Involved in the cleavage of the adhesion molecule L1 at the cell surface and in released membrane vesicles, suggesting a vesicle-based protease activity. Controls also the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis. Responsible for the FasL ectodomain shedding and for the generation of the remnant ADAM10-processed FasL (FasL APL) transmembrane form. Also cleaves the ectodomain of the integral membrane proteins CORIN and ITM2B. May regulate the EFNA5-EPHA3 signaling.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human Disintegrin and metalloproteinase domain-containing protein 10 protein (214-504AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 28.08.2025

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