E2F4 Antibody, HRP conjugated

Polyclonal Antibody

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Human

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.

>95%, Protein G purified

Epigenetics and Nuclear Signaling

Recombinant Human Transcription factor E2F4 protein (160-299AA)