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MCC Antibody, FITC conjugated

MCC Antibody, FITC conjugated

ArtNr	CSB-PA013571LC01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 50 ug
Kategorie	Oncology Antibodies ELISA Primary Antibodies By Organ Skin Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	FITC
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Colorectal mutant cancer protein antibody; CRCM_HUMAN antibody; DKFZp762O1615 antibody; FLJ38893 antibody; FLJ46755 antibody; MCC 1 antibody; MCC antibody; MCC1 antibody; Mutated in colorectal cancers antibody; Protein MCC antibody
Similar products	MCC, Colorectal mutant cancer protein (Protein MCC)
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	MCC
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Recombinant Human Colorectal mutant cancer protein (479-611AA)
Background	Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation (PubMed:18591935, PubMed:19555689, PubMed:22480440). Represses the beta-catenin pathway (canonical Wnt signaling pathway) in a CCAR2-dependent manner by sequestering CCAR2 to the cytoplasm, thereby impairing its ability to inhibit SIRT1 which is involved in the deacetylation and negative regulation of beta-catenin (CTNB1) transcriptional activity (PubMed:24824780).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cancer
Initial Research Areas	Cancer
Antigen Species	Human
Antigen	Recombinant Human Colorectal mutant cancer protein (479-611AA)
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-PA013571LC01HU-50ug-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 28.08.2025

Express-Lieferung: 3 Tage sparen

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