PBX1 Antibody

ArtNr	CSB-PA017505LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Hematology Leukemia Lymphoma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies By Organ Bladder Cancer Heart & Blood Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DKFZp686B09108 antibody; Homeo box protein PBX1 antibody; Homeo box protein PRL antibody; Homeobox protein PBX 1 antibody; Homeobox protein PBX1 antibody; Homeobox protein PRL antibody; MGC126627 antibody; PBX 1 antibody; Pbx1 antibody; PBX1_HUMAN antibody; Pre B cell leukemia homeobox 1 antibody; Pre B cell leukemia transcription factor 1 antibody; Pre-B-cell leukemia transcription factor 1 antibody; PRL antibody
Similar products	PRL, PBX1, Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	PBX1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	DKFZp686B09108 antibody; Homeo box protein PBX1 antibody; Homeo box protein PRL antibody; Homeobox protein PBX 1 antibody; Homeobox protein PBX1 antibody; Homeobox protein PRL antibody; MGC126627 antibody; PBX 1 antibody; Pbx1 antibody; PBX1_HUMAN antibody; Pre B cell leukemia homeobox 1 antibody; Pre B cell leukemia transcription factor 1 antibody; Pre-B-cell leukemia transcription factor 1 antibody; PRL antibody
Immunogen Species	Human
Immunogen	Recombinant Human Pre-B-cell leukemia transcription factor 1 protein (315-430AA)
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:5000 IHC:1:100-1:300 IF:1:50-1:200
Background	Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1, 19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression (By similarity).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Pre-B-cell leukemia transcription factor 1 protein (315-430AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 04.09.2025

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