SSTR2 Antibody

ArtNr	CSB-PA022725LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Blastoma Carcinoma Glioma Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Somatostatin receptor type 2 antibody; SRIF-1 antibody; SRIF1 antibody; SS-2-R antibody; SS2-R antibody; SS2R antibody; SSR2_HUMAN antibody; SST2 antibody; SSTR2 antibody
Similar products	SSTR2, Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	SSTR2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Recombinant Human Somatostatin receptor type 2 protein (304-369AA)
Dilution	ELISA:1:2000-1:10000 WB:1:1000-1:5000 IHC:1:20-1:200 IF:1:50-1:200
Background	Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Neuroscience
Initial Research Areas	Neuroscience
Antigen Species	Human
Antigen	Recombinant Human Somatostatin receptor type 2 protein (304-369AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 6 Tage sparen

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