U2AF2 Antibody

ArtNr	CSB-PA025408LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	hU2AF(65) antibody; hU2AF65 antibody; Splicing factor U2AF 65 kDa subunit antibody; U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody; U2 auxiliary factor 65 kDa subunit antibody; U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody; U2 small nuclear RNA auxiliary factor 2 antibody; U2 snRNP auxiliary factor large subunit antibody; U2af2 antibody; U2AF2_HUMAN antibody; U2AF65 antibody
Similar products	U2AF2, U2AF65, Splicing factor U2AF 65 kDa subunit (U2 auxiliary factor 65 kDa subunit) (hU2AF(65)) (hU2AF65) (U2 snRNP auxiliary factor large subunit)
Lieferbar
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	U2AF2
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	hU2AF(65) antibody; hU2AF65 antibody; Splicing factor U2AF 65 kDa subunit antibody; U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody; U2 auxiliary factor 65 kDa subunit antibody; U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody; U2 small nuclear RNA auxiliary factor 2 antibody; U2 snRNP auxiliary factor large subunit antibody; U2af2 antibody; U2AF2_HUMAN antibody; U2AF65 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Splicing factor U2AF 65 kDa subunit protein (124-246AA)
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:5000
Background	Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Splicing factor U2AF 65 kDa subunit protein (124-246AA)
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 ug

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Lieferung vsl. bis 11.09.2025

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