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LRRC32 Antibody, Biotin conjugated

LRRC32 Antibody, Biotin conjugated

ArtNr	CSB-PA618886LD01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 50 ug
Kategorie	Antibodies ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Biotin
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	D11S833E antibody; GARP antibody; Garpin antibody; Glycoprotein A repetitions predominant antibody; Leucine rich repeat containing 32 antibody; Leucine-rich repeat-containing protein 32 antibody; LRC32_HUMAN antibody; LRRC32 antibody
Similar products	LRRC32, D11S833E, Transforming growth factor beta activator LRRC32 (Garpin) (Glycoprotein A repetitions predominant) (GARP) (Leucine-rich repeat-containing protein 32)
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	LRRC32
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Immunogen Species	Human
Immunogen	Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
Background	Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742). Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742). Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742). Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619). Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Others
Antigen Species	Human
Antigen	Recombinant Human Transforming growth factor beta activator LRRC32 protein (301-500AA)
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-PA618886LD01HU-50ug-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 28.08.2025

Express-Lieferung: 3 Tage sparen

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