ACD Antibody

ArtNr	CSB-PA839289LA01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Acd antibody; ACD_HUMAN antibody; Adrenocortical dysplasia homolog antibody; Adrenocortical dysplasia protein homolog antibody; PIP1 antibody; POT1 and TIN2 organizing protein antibody; POT1 and TIN2-interacting protein antibody; TIN2 interacting protein 1 antibody; TINT1 antibody; TPP1 antibody
Similar products	ACD, Adrenocortical dysplasia protein homolog (POT1 and TIN2-interacting protein), PIP1 PTOP TINT1 TPP1
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	ACD
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	Acd antibody; ACD_HUMAN antibody; Adrenocortical dysplasia homolog antibody; Adrenocortical dysplasia protein homolog antibody; PIP1 antibody; POT1 and TIN2 organizing protein antibody; POT1 and TIN2-interacting protein antibody; TIN2 interacting protein 1 antibody; TINT1 antibody; TPP1 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA)
Dilution	ELISA:1:2000-1:10000 WB:1:500-1:5000
Background	Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA)
Clonality	Polyclonal

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Menge: 50 ug

lieferbar

Lieferung vsl. bis 11.09.2025