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MBD1 Antibody, Biotin conjugated

MBD1 Antibody, Biotin conjugated

ArtNr	CSB-PA883444LD01HU-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 50 ug
Kategorie	Neuroscience Targets for Rodent Neurosciences Antibodies ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Biotin
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; Methyl CpG binding domain protein 1 antibody; Methyl CpG binding domain protein 1 isoform PCM1 antibody; Methyl CpG binding protein MBD1 antibody; Methyl CpG binding protein splice variant 1 antibody; Methyl CpG binding protein splice variant 2 antibody; Methyl CpG binding protein splice variant 3 antibody; Methyl CpG binding protein splice variant 4 antibody; Methyl-CpG-binding domain protein 1 antibody; Methyl-CpG-binding protein MBD1 antibody; PCM 1 antibody; PCM1 antibody; Protein containing methyl-CpG-binding domain 1 antibody; Regulator of fibroblast growth factor 2 (FGF 2) transcription antibody; RFT antibody; The regulator of fibroblast growth factor 2(FGF 2) transcription antibody
Similar products	MBD1, Methyl-CpG-binding domain protein 1 (CXXC-type zinc finger protein 3) (Methyl-CpG-binding protein MBD1) (Protein containing methyl-CpG-binding domain 1), CXXC3 PCM1
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	MBD1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	CXXC 3 antibody; CXXC-type zinc finger protein 3 antibody; CXXC3 antibody; MBD 1 antibody; Mbd1 antibody; MBD1_HUMAN antibody; MECP1 COMPLEX antibody; Methyl CpG binding domain protein 1 antibody; Methyl CpG binding domain protein 1 isoform PCM1 antibody; Methyl CpG binding protein MBD1 antibody; Methyl CpG binding protein splice variant 1 antibody; Methyl CpG binding protein splice variant 2 antibody; Methyl CpG binding protein splice variant 3 antibody; Methyl CpG binding protein splice variant 4 antibody; Methyl-CpG-binding domain protein 1 antibody; Methyl-CpG-binding protein MBD1 antibody; PCM 1 antibody; PCM1 antibody; Protein containing methyl-CpG-binding domain 1 antibody; Regulator of fibroblast growth factor 2 (FGF 2) transcription antibody; RFT antibody; The regulator of fibroblast growth factor 2(FGF 2) transcription antibody
Immunogen Species	Human
Immunogen	Recombinant Human Methyl-CpG-binding domain protein 1 protein (106-355AA)
Background	Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting AFT7IP, which in turn recruits factors such as the histone methyltransferase SETDB1. Probably forms a complex with SETDB1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Isoform 1 and isoform 2 can also repress transcription from unmethylated promoters.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Methyl-CpG-binding domain protein 1 protein (106-355AA)
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 ug

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Lieferung vsl. bis 28.08.2025

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