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Anti-GITR antibody(DM78); Rabbit mAb

ArtNr DIM-DME100078-10uL
Hersteller DIMA Biotechnology
Menge 10 uL
Quantity options 100 uL 100 ug 10 uL 10 ug 500 ug
Kategorie
Typ Antibody Primary
Format Lyophilized
Applikationen FC, ELISA
Clon DM78
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias AITR,GITR,TNFRSF18,CD357
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Monoclonal antibodies
Manufacturer - Targets
GITR
Molecular Weight
26.0kDa
Buffer
50% Glycerol; PBS, pH 7.4; 0.1% BSA
Clonality
Monoclonal
Purification
Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions
ELISA 1:5000-10000; Flow Cyt 1:100
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25( )CD4( ) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Immunogen
Recombinant human GITR (Gln266-Pro162) (PME100018) produced by using human HEK293 cells
Antigen
GITR
Application Advice
ELISA 1/5000-10000; Flow Cyt 1/100
Description
Anti-GITR antibody(DM78); Rabbit mAb
Preservative
0.1% Procline 300
Reconstitution
Reconstitute with deionized water
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Usage
Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 uL
Lieferbar: In stock
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