VIL1 antibody

ArtNr	FNab09407-100ug
Hersteller	FineTest
Menge	100 ug
Quantity options	100 ug 100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IF, IP, IHC, ELISA
Clon	3D11
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Mouse
Isotype	IgG1
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Villin-1,VIL1,VIL
Lieferbar
Manufacturer - Targets	VIL1
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
Background	Villin 1(VIL1) is a 95-kd F-actin bundling and severing protein and its expression is restricted to epithelial cells with a brush border, like epithelial cells of the intestinal mucosa, gall bladder, renal proximal tubules and ductuli efferentes of the testis. VIL1 has been reported to be an epithelial cell-specific anti-apoptotic protein, and to have an important function in regulating actin dynamics, cell morphology, epithelial-to-mesenchymal transitions, cell migration and cell survival. In addition, VIL1 is a useful diagnostic marker for of various cancer, like cervical and endometrial adenocarcinomas, renal cell carcinoma. VIL1 was recently identified as a novel biomarker predictive for postoperative recurrence and poorer prognosis of high serum AFP associated HCC.
Clonality	monoclonal
Immunogen	villin 1
Observed MW	93 kDa
Purification	Protein A+G purification
Recommended dilution	WB: 1:500-1:5000; IHC: 1:50-1:2000; IF: 1:10-1:100; IP: 1:500-1:5000
Manufacturer - Research Area	Cancer, Immunology

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