ZAP70 antibody

ArtNr	FNab09582-100ug
Hersteller	FineTest
Menge	100 ug
Quantity options	100 ug 100 ug 100 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Purity	≥95% as determined by SDS-PAGE
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tyrosine-protein kinase ZAP-70,70 kDa zeta-chain associated protein,Syk-related tyrosine kinase,ZAP70,SRK
Lieferbar
Manufacturer - Targets	ZAP70
Storage Conditions	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Background	This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Clonality	polyclonal
Immunogen	zeta-chain (TCR) associated protein kinase 70kDa
Observed MW	69 kDa
Purification	Immunogen affinity purified
Recommended dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Manufacturer - Research Area	Immunology, Signal Transduction, Metabolism, Developmental biology

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