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Etanercept Biosimilar - Research Grade Europäischer Partner

ArtNr ICH4022-5MG
Hersteller IchorBio
Menge 5mg
Kategorie
Typ Biosimilars
Specific against Human
Host Humanized
Purity >95% by SDS-PAGE and HPLC
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Tumor necrosis factor
Lieferbar
Specificity Detects human TNF. This non-therapeutic fusion-protein uses the same variable region sequence as the therapeutic Etanercept. This product is for research use only.
Manufacturers Product Category
Low endotoxin, biosimilar protein
Host Information
Humanized
Purification method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background
Etanercept biosimilar is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept biosimilar is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons.
Concentration
1.0 - 5.0 mg/ml
Formulation
Phosphate buffered saline (PBS) pH 7.2, with no carrier protein, potassium or preservatives added. BSA and Azide free.
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 5mg
Lieferbar: In stock
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