« Zurück
Startseite /
Anti-Human FGF R3 (Clone 136312) - 25 µg

Anti-Human FGF R3 (Clone 136312) - 25 µg

ArtNr	LEIN-F1085-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	100 ug 25 ug 500 ug
Kategorie	Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Typ	Antibody Monoclonal
Applikationen	WB, IHC, ICC
Clon	136312
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Hicks, D. et al. (1999) J Mol Neurosci. 13: 187 2. Hartmann, A. et al. (2006) J Clin Invest. 116(8):2201-2207. 3. Radvanyi, F. et al. (2005) Human Molecular Genetics 14: 1153
NCBI	2261
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	ICC, IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	FGF R3
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Fibroblast growth factor receptor 3 is receptor tyrosine kinases expressed on most types of cells.1 FGFR3 protein plays a role in the development and maintenance of bone and brain tissue and has several important cellular functions such as regulation of cell growth and division, determination of cell type, formation of blood vessels, wound healing, and embryo development.2 FGFR3 result in autosomal dominant human skeletal dysplasias and is a major cause of benign epidermal tumors in humans.3
Background	Fibroblast growth factor receptor 3 is receptor tyrosine kinases expressed on most types of cells.¹ FGFR3 protein plays a role in the development and maintenance of bone and brain tissue and has several important cellular functions such as regulation of cell growth and division, determination of cell type, formation of blood vessels, wound healing, and embryo development.² FGFR3 result in autosomal dominant human skeletal dysplasias and is a major cause of benign epidermal tumors in humans.³
Other Applications Reported In Literature	IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 25 µg/ml. The recommended secondary antibody for IHC is PN:M114. For chromogenic detection with high signal and low background use PN:D100 or PN:K107. Immunocytochemistry: Suitable for use at concentration of 8-25 µg/mL.
PubMed	FGF R3
Manufacturer - Specificity	Mouse Anti-Human Fibroblast Growth Factor Receptor 3 (FGF R3) (Clone 136312) recognizes an epitope on Human FGF R3. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2830131
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen	Sf 21-Derived and NS0-Derived Extracellular Domains of Recombinant Human FGF R3 Isoforms
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Fibroblast Growth Factor Receptor 3, ACH, Cluster of Differentiation 33 (CD333), CEK2, HSFGFR3EX, JTK4, 136312, FGF R3, Human, Anti-Human FGF R3 (IIIc), CD333, CEK, EC 2.7.10, FGF R3, FGFR3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

LEIN-F1085-25ug-safety-datasheet.pdf