« Back
Home /
Anti-Human FGF R3 (Clone 136312) - 25 µg

Anti-Human FGF R3 (Clone 136312) - 25 µg

Item no.	LEIN-F1085-25ug
Manufacturer	Leinco Technologies
Amount	25 ug
Quantity options	100 ug 25 ug 500 ug
Category	Antibodies Immunohistochemistry Western Blot Immunocytochemistry Primary Antibodies Immunochemistry
Type	Antibody Monoclonal
Applications	WB, IHC, ICC
Clone	136312
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Hicks, D. et al. (1999) J Mol Neurosci. 13: 187 2. Hartmann, A. et al. (2006) J Clin Invest. 116(8):2201-2207. 3. Radvanyi, F. et al. (2005) Human Molecular Genetics 14: 1153
NCBI	2261
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Shipping Condition	Room temperature
Available
Manufacturer - Applications	ICC, IHC FFPE, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	FGF R3
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Fibroblast growth factor receptor 3 is receptor tyrosine kinases expressed on most types of cells.1 FGFR3 protein plays a role in the development and maintenance of bone and brain tissue and has several important cellular functions such as regulation of cell growth and division, determination of cell type, formation of blood vessels, wound healing, and embryo development.2 FGFR3 result in autosomal dominant human skeletal dysplasias and is a major cause of benign epidermal tumors in humans.3
Background	Fibroblast growth factor receptor 3 is receptor tyrosine kinases expressed on most types of cells.¹ FGFR3 protein plays a role in the development and maintenance of bone and brain tissue and has several important cellular functions such as regulation of cell growth and division, determination of cell type, formation of blood vessels, wound healing, and embryo development.² FGFR3 result in autosomal dominant human skeletal dysplasias and is a major cause of benign epidermal tumors in humans.³
Other Applications Reported In Literature	IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 25 µg/ml. The recommended secondary antibody for IHC is PN:M114. For chromogenic detection with high signal and low background use PN:D100 or PN:K107. Immunocytochemistry: Suitable for use at concentration of 8-25 µg/mL.
PubMed	FGF R3
Manufacturer - Specificity	Mouse Anti-Human Fibroblast Growth Factor Receptor 3 (FGF R3) (Clone 136312) recognizes an epitope on Human FGF R3. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2830131
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen	Sf 21-Derived and NS0-Derived Extracellular Domains of Recombinant Human FGF R3 Isoforms
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Fibroblast Growth Factor Receptor 3, ACH, Cluster of Differentiation 33 (CD333), CEK2, HSFGFR3EX, JTK4, 136312, FGF R3, Human, Anti-Human FGF R3 (IIIc), CD333, CEK, EC 2.7.10, FGF R3, FGFR3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

LEIN-F1085-25ug-safety-datasheet.pdf