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Anti-Mouse γ/δ (TCR) - PE

Anti-Mouse γ/δ (TCR) - PE

ArtNr	LEIN-T132-200ug
Hersteller	Leinco Technologies
Menge	200 ug
Quantity options	100 ug 200 ug 50 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Clon	UC7-13D5
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Citations	Bluestone, J. A. et al. (1991) Immunol. Rev. 120:5
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Mouse T-Cell Receptor Complex
Manufacturer - Targets	γ/δ T-Cell Receptor
Country of Origin	USA
Shipping Temperature	Next Day 2-8°C
Storage Conditions	This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Background	The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
PubMed	γ/δ T-Cell Receptor
Excitation Laser	Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Manufacturer - Research Area	Adaptive Immunity, Immunology
Manufacturer - Specificity	The anti-mouse γ/δ T-cell receptor antibody reacts with all mouse TCR γ/δ heterodimers.
RRID	AB_2894341
Concentration	0.2 mg/ml
Formulation	This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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LEIN-T132-200ug-safety-datasheet.pdf