PCDH12 Antibody

blue ice or room temperature

Predicted: 128 kDa
Observed: 125 kDa

PCDH12 Antibody: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2, 289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.

PCDH12 Antibody is affinity chromatography purified via peptide column.

1 mg/ml

PCDH12 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human PCDH12.

The immunogen is located within amino acids 30 - 80 of PCDH12.

protocadherin 12

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.