ZMYM4 Antibody

ArtNr	PRS-6139-0.02mg
Hersteller	ProSci
Menge	0.02 mg
Quantity options	0.02 mg 0.1 mg
Kategorie	Oncology Antibodies Immunohistochemistry ELISA Primary Antibodies By Organ Lung Cancer Skin Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	ELISA, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Rosenfeld R and Margalit H. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. J. Biomol. Struct. Dyn. 1993; 11:557-70. Gregory SG, Barlow KF, McLay KE, et al. The DNA sequence and biological annotation of human chromosome 1. Nature 2006; 441:315-21. Sohal J, Reiter A, Goldman JM, et al. Cloning of ZNF237, a novel member of the MYM gene family that maps to human chromosome 13q11→q12. Cytogenet. Cell Genet. 2000; 89:24-8. McDoniels-Silvers AL, Nimri CF, Stoner GD, et al. Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas. Clin. Cancer Res. 2002; 8:1127-38.
NCBI	ZMYM4
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ZMYM4 Antibody: MYM,CDIR,ZNF262,ZNF198L3,KIAA0425,Zinc finger MYM-type protein 4,Zinc finger protein 262
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	ZMYM4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	167 kDa
Manufacturer - Research Area	Cancer, Cell Cycle
Background	ZMYM4 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-γ -induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.
By Type	Cancer, Cell Cycle
Badges	Trial Size
Modifications	None
Protein Gi #	117558167
Purification	ZMYM4 Antibody is affinity chromatography purified via peptide column.
Concentration	1 mg/mL
Buffer	ZMYM4 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note	ZMYM4 antibody can be used for detection of ZMYM4 by immunohistochemistry at 5 μ g/mL. Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Homology	Predicted species reactivity based on immunogen sequence: Mouse: (94%)
Manufacturer - Specificity	At least three isoforms of ZMYM4 are known to exist; this antibody will detect all of them. ZMYM4 antibody is predicted not to cross-react with other ZMYM family members.
Immunogen	ZMYM4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM4. The immunogen is located within the last 50 amino acids of ZMYM4.
Clonality	Polyclonal
NCBI Official Name	zinc finger, MYM-type 4
NCBI Organism	homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.02 mg

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