Comparison

ZMYM4 Antibody

Item no. PRS-6139-0.02mg
Manufacturer ProSci
Amount 0.02 mg
Quantity options 0.02 mg 0.1 mg
Category
Type Antibody Polyclonal
Format Liquid
Applications ELISA, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Conjugate/Tag Unconjugated
Citations Rosenfeld R and Margalit H. Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. J. Biomol. Struct. Dyn. 1993; 11:557-70.
Gregory SG, Barlow KF, McLay KE, et al. The DNA sequence and biological annotation of human chromosome 1. Nature 2006; 441:315-21.
Sohal J, Reiter A, Goldman JM, et al. Cloning of ZNF237, a novel member of the MYM gene family that maps to human chromosome 13q11→q12. Cytogenet. Cell Genet. 2000; 89:24-8.
McDoniels-Silvers AL, Nimri CF, Stoner GD, et al. Differential gene expression in human lung adenocarcinomas and squamous cell carcinomas. Clin. Cancer Res. 2002; 8:1127-38.
NCBI ZMYM4
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias ZMYM4 Antibody: MYM,CDIR,ZNF262,ZNF198L3,KIAA0425,Zinc finger MYM-type protein 4,Zinc finger protein 262
Shipping Condition Cool pack
Available
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
ZMYM4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
167 kDa
Manufacturer - Research Area
Cancer, Cell Cycle
Background
ZMYM4 Antibody: Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. It has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas, and the overexpression of a fragment of the 3'UTR of the ZMYM4 mRNA termed Cell Death Inhibiting RNA (CDIR) protects HeLa cells from IFN-γ -induced apoptosis, suggesting that ZMYM4 may play a role in tumorigenesis.
By Type
Cancer, Cell Cycle
Badges
Trial Size
Modifications
None
Protein Gi #
117558167
Purification
ZMYM4 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Buffer
ZMYM4 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
ZMYM4 antibody can be used for detection of ZMYM4 by immunohistochemistry at 5 μ g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (94%)
Manufacturer - Specificity
At least three isoforms of ZMYM4 are known to exist; this antibody will detect all of them. ZMYM4 antibody is predicted not to cross-react with other ZMYM family members.
Immunogen
ZMYM4 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human ZMYM4.

The immunogen is located within the last 50 amino acids of ZMYM4.
Clonality
Polyclonal
NCBI Official Name
zinc finger, MYM-type 4
NCBI Organism
homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 0.02 mg
Available: In stock
available

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