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GAPDH Antibody [12D3H9]

ArtNr PRS-PM-7571-0.02mg
Hersteller ProSci
Menge 0.02 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ELISA
Clon 12D3H9
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Mouse
Isotype IgG
Konjugat/Tag Unconjugated
Citations Sirover MA. New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J. Cell. Biochem. 2005; 95:45-52.
Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annu. Rev. Pharmacol. Toxicol. 2005; 45:269-90.
NCBI GAPDH
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Glyceraldehyde-3-phosphate dehydrogenase, G3PDH, GAPD
Lieferbar
Manufacturer - Applications
GAPDH antibody can be used for detection of GAPDH by Western blot at 1 - 2 μg/ml.

Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested.
Shipping Temperature
blue ice or room temperature
Storage Conditions
GAPDH antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Molecular Weight
Predicted: 37 kDa
Observed: 36 kDa
Manufacturer - Research Area
Signal Transduction, Neuroscience, Homeostasis
Background
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. It also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH also plays a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
Protein Gi #
7669492
Purification
GAPDH antibody is Protein A purified.
Positive Control 1
Concentration
1 mg/ml
Buffer
GAPDH antibody is supplied in PBS containing 0.02% sodium azide.
Homology
Predicted species reactivity based on immunogen sequence: Pig: (100%), Guinea pig: (100%), Sheep: (93%), Bovine: (93%), Chicken: (93%), Rabbit: (93%)
Immunogen
GAPDH antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GAPDH.

The immunogen is located within amino acids 230 - 280 of GAPDH.
Clonality
Monoclonal
NCBI Official Name
glyceraldehyde-3-phosphate dehydrogenase
NCBI Organism
homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
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