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Rabbit anti-MTOR Polyclonal Antibody

Rabbit anti-MTOR Polyclonal Antibody

ArtNr	RD71489A-60uL
Hersteller	Reddot Biotech
Menge	60 uL
Quantity options	120 uL 200 uL 20 uL 60 uL
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, ELISA, IHC-P
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	dJ576K7.1 (FK506 binding protein 12 rapamycin associated protein 1),FK506 binding protein 12 rapamycin associated protein 1,FK506 binding protein 12 rapamycin associated protein 2,FK506 binding protein 12 rapamycin complex associated protein 1,FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP rapamycin associated protein,FKBP12 rapamycin complex associated protein,FKBP12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,FLJ44809,FRAP,FRAP1,FRAP2,Mammalian target of rapamycin,Mechanistic target of rapamycin,mTOR,MTOR,OTTHUMP00000001983,RAFT1,Rapamycin and FKBP12 target 1,Rapamycin associated protein FRAP2,Rapamycin target protein 1,Rapamycin target protein,RAPT1,Serine/threonine-protein kinase mTOR
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Storage Conditions	Store at -20°C. Avoid repeated freeze / thaw cycles.
Background	MTOR, also named as FRAP1, FRAP, FRAP2 and RAPT1, belongs to the PI3/PI4-kinase family. MTOR is a Ser/Thr protein kinase that functions as an ATP and amino acid sensor to balance nutrient availability and cell growth. MTOR is Kinase subunit of both mTORC1 and mTORC2, which regulate cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. The antibody is specific to MTOR.
Concentration	1mg/mL
Immunogen	Synthesized peptide derived from human mTOR around the non-phosphorylation site of Ser2481.
Buffer	PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Purification Method	Affinity purification
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Clonality	Polyclonal

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 60 uL

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Lieferung vsl. bis 28.08.2025

Express-Lieferung: 3 Tage sparen

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