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Phospho-RPS6KB1-T421/S424 Antibody kit (AP1106 & A16968) Europäischer Partner

ArtNr RK05805-200ul
Hersteller Abclonal
Menge 200 ul
Quantity options 100 ul 200 ul 20 ul 50 ul
Kategorie
Typ Antibody
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Purity Affinity purification
Sequence AP1106,A16968
NCBI RPS6KB1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Other
Shipping Temperature
ice pack
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]
Immunogen
A phospho specific peptide corresponding to residues surrounding T421/S424 of human RPS6KB1.
Recommended Dilution
AP1106, WB, 1:500 - 1:2000|A16968, WB, 1:500 - 1:2000
Protein Size
51kDa/52kDa/56kDa/59kDa
Route
Synthetic peptide
Manufacturer - Research Area
AMPK Signaling Pathway, Angiogenesis, Apoptosis, Apoptosis_Inhibition of Apoptosis, Apoptosis_Mitochondrial Control of Apoptosis, B Cell Receptor Signaling Pathway, Cardiovascular, Cell Biology & Developmental Biology, Cell Cycle, Cell Cycle_Cell cycle inhibitors, DNA Damage & Repair, Endocrine & Metabolism, Endocrine and metabolic diseases, Endocrine and metabolic diseases_Obesity, Epigenetics & Nuclear Signaling, ErbB-HER Signaling Pathway, Immunology & Inflammation, Insulin Receptor Signaling Pathway, Kinase, Kinase_Serine/threonine kinases, mTOR Signaling Pathway, PI3K-Akt Signaling Pathway, PI3K-Akt Signaling Pathway_Akt downstream targets, Protein Kinase C Signaling Pathway Pathway, Protein phosphorylation, Signal Transduction, TGF-b-Smad Signaling Pathway, Translation Control, Translational Control_Regulation of eIF4 and p70 S6 Kinase,

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200 ul
Lieferbar: In stock
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