Anti-GSTM1 Antibody Picoband® (monoclonal, 11F2)

Mouse IgG1

26 kDa

Western blot, 0.1-0.5?g/ml

Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml

Immunohistochemistry (Frozen Section), 0.5-1?g/ml

Immunocytochemistry, 0.5-1?g/ml

Flow Cytometry (Fixed), 1-3?g/1x106 cells

glutathione S-transferase mu 1

Glutathione S-transferase Mu 1 (gene name GSTM1) is a human glutathione S-transferase. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Each vial contains 4 mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.

Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.

Boster Bio Anti-GSTM1 Antibody Picoband® (monoclonal, 11F2) catalog # M00569. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.