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Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody

Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody

ArtNr	BOS-M00953-1
Hersteller	Boster
Menge	100 ul
Kategorie	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IP, IHC
Clon	FB-20
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	DNA topoisomerase 2-alpha;5.99.1.3;DNA topoisomerase II, alpha isozyme;TOP2A;TOP2;
Lieferbar
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	28 kDa
Calculated Molecular weight	174385 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:2000 IHC 1:50-1:200 IP 1:50
Manufacturer - Gene Name	TOP2A
Gene Full Name	DNA topoisomerase 2-alpha
Immunogen	A synthesized peptide derived from human Topoisomerase II alpha
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Cancer, Chromosome Structure, DNA/RNA, DNA Synthesis, Epigenetics and Nuclear Signaling
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
Subcellular Localization	Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.
Description	Boster Bio Anti-Topoisomerase II alpha TOP2A Rabbit Monoclonal Antibody catalog # M00953-1. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in the excretory system, thyroid gland and Wilms tumors.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M00953-1-datasheet.pdf

BOS-M00953-1-safety-datasheet.pdf