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Anti-Zyxin Monoclonal Antibody Europäischer Partner

ArtNr BOS-M02365
Hersteller Boster
Menge 100 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, IF, IP, IHC, ICC
Clon AFOG-26
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity >5000 cells
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Phosphatidylinositol 3-kinase catalytic subunit type 3;PI3-kinase type 3;PI3K type 3;PtdIns-3-kinase type 3;2.7.1.137;Phosphatidylinositol 3-kinase p100 subunit;Phosphoinositide-3-kinase class 3;hVps34;PIK3C3;VPS34;
Lieferbar
Manufacturer - Category
Rabbit Monoclonal Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
78 kDa
Calculated Molecular weight
101549 MW
Clonality
Monoclonal
Application Details
WB 1:1000-1:5000
IHC 1:50-1:200
ICC/IF 1:50-1:200
IP 1:50
FC 1:500
Manufacturer - Gene Name
ZYX
Gene Full Name
Phosphatidylinositol 3-kinase catalytic subunit type 3
Immunogen
A synthesized peptide derived from human Zyxin.
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category
Actin, Actin Binding Proteins, Actin, etc., Cell Adhesion Proteins, Cytoskeleton, Cytoskeleton/ECM, ECM Proteins, Epigenetics and Nuclear Signaling, Microfilaments, Neuroscience, Signal Transduction, Transcription, Transcription Factors
Protein Name
Lysosome-associated membrane glycoprotein 2 (Lamp2)
Protein Function
Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).
Subcellular Localization
Midbody. Late endosome. Cytoplasmic vesicle, autophagosome. As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes (Probable). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme (By similarity).
Description
Boster Bio Anti-Zyxin Monoclonal Antibody catalog # M02365. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Ubiquitously expressed, with a highest expression in skeletal muscle.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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