Comparison

Anti-CXCR2 Antibody Picoband® European Partner

Item no. BOS-PA1029
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB
Specific against Human (Homo sapiens), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Citations 1. Murphy P.M., Tiffany H.L.;"Cloning of complementary DNA encoding a functional human interleukin-8 receptor."; Science 253:1280-1283(1991).
2. Cerretti D.P., Kozlosky C.J., Vanden Bos T., Nelson N., Gearing D.P., Beckmann M.P.;
"Molecular characterization of receptors for human interleukin-8, GRO/melanoma growth-stimulatory activity and neutrophil activating peptide-2."; Mol. Immunol. 30:359-367(1993).
3. Sprenger H., Lloyd A.R., Lautens L.L., Bonner T.I., Kelvin D.J.;"Structure, genomic organization, and expression of the human interleukin-8 receptor B gene.";J. Biol. Chem. 269:11065-11072(1994).
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias C-X-C chemokine receptor type 2;CXC-R2;CXCR-2;CDw128b;GRO/MGSA receptor;High affinity interleukin-8 receptor B;IL-8R B;IL-8 receptor type 2;CD182;CXCR2;IL8RB;
Similar products C-X-C chemokine receptor type 2 antibody, CD 182 antibody, CD182 antibody, CD182 antigen antibody, CDw128b antibody, Chemokine(CXC) receptor 2 antibody, CMKAR2 antibody, CXC-R2 antibody, CXCR 2 antibody, CXCR-2 antibody, CXCR2 antibody, CXCR2_HUMAN antibody, GRO/MGSA receptor antibody, High affinity interleukin-8 receptor B antibody, IL 8 receptor type 2 antibody, IL 8R B antibody, IL-8 receptor type 2 antibody, IL-8R B antibody, IL8 RB antibody, IL8 receptor type 2 antibody, IL8R B antibody, IL8R2 antibody, IL8RA antibody, Interleukin 8 Receptor B antibody
Available
Specificity No cross reactivity with other proteins.
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
45 kDa
Calculated Molecular weight
40759 MW
Clonality
Polyclonal
Application Details
Western blot, 0.1-0.5?g/ml, Human, Rat
Manufacturer - Gene Name
CXCR2
Gene Full Name
C-X-C chemokine receptor type 2
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
CXCR2 is a receptor for Interleukin 8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family (subfamily, chemokine). Binding of IL8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL8 with a high affinity and to GRO/MGSA and NAP2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human CXCR2, different from the related mouse sequence by six amino acids.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Cell Biology, Cell Cycle, Cell Division, G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Name
C-X-C chemokine receptor type 2(CXC-R2/CXCR-2)
Protein Function
Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Subcellular Localization
Cell membrane; Multi-pass membrane protein.
Description
Boster Bio Anti-CXCR2 Antibody catalog # PA1029. Tested in WB applications. This antibody reacts with Human, Rat.
Tissue Specificity
Found in plasma.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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