Recombinant Human Endostatin

Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 100 ug
ArtNr CS-CRE301B
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Recombinant Human Endostatin, produced in Pichia Pastoris, is a single, glycosylated, polypeptide having a total molecular mass of 20, 000 Dalton C-terminal fragment of collagen XVIII that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Induces tyrosine phosphorylation of Shc (SH2 domain adapter protein) leading to specific inhibition in endothelial cell prolifiration. The recombinant Human Endostatin is purified by proprietary chromatographic techniques.
Source
Pichia Pastoris
Purity
Greater than 98.0% as detmined by: (a) Analysis by RP-HPLC. (b) Anion-exchange FPLC. (c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained.
Endotoxin Level
Less than 0.1 ng/ug (IEU/ug) of recombinant Human Endostatin.
Biological Activity
Recombinant Human Endostatin is fully biologically active when compared to standards. The activity calculated by ECE migration inhibition was found to be 50, 000 IU/mg.
Format
Sterile filtered liquid formulation
Menge: 100 ug
Lieferbar: In stock
Listenpreis: 428,68 €
Preis: 428,68 €
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