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Recombinant Human Endostatin

Recombinant Human Endostatin

Manufacturer	Cell Sciences
Category	Neuroscience Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins Cell Biology Cell Stainings ECM
Type	Proteins
Specific against	Human
Format	Sterile filtered liquid formulation
Amount	100 ug
Item no.	CS-CRE301B
eClass 6.1	34160400
eClass 9.0	42020190
Available
Biological Activity	Recombinant Human Endostatin is fully biologically active when compared to standards. The activity calculated by ECE migration inhibition was found to be 50, 000 IU/mg.
Description	Recombinant Human Endostatin, produced in Pichia Pastoris, is a single, glycosylated, polypeptide having a total molecular mass of 20, 000 Dalton C-terminal fragment of collagen XVIII that has been shown to act as a potent inhibitor of angiogenesis and tumor growth in vitro and in vivo. Induces tyrosine phosphorylation of Shc (SH2 domain adapter protein) leading to specific inhibition in endothelial cell prolifiration. The recombinant Human Endostatin is purified by proprietary chromatographic techniques.
Endotoxin Level	Less than 0.1 ng/ug (IEU/ug) of recombinant Human Endostatin.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.