Recombinant Human RXRA

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Hersteller Cell Sciences
Kategorie
Typ Proteins
Specific against Human
Menge 50 ug
Host E.coli
ArtNr CS-CRR111B
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
Recombinant human RXRA is a single, non-glycosylated polypeptide chain containing 119 amino acids. The DNA binding domain of RXR (aa 111-228) was purified by using conventional column chromatography techniques. The retinoid X receptor (RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partners. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors (RAR), thyroid hormone receptors (TR), vitamin D receptors and peroxisome proliferators-activated receptors (PPAR). The RXR family includes three difference isoforms, RXR A, B, and G. Human RXRA gene is localized on 9q34.9 and encodes two major isoforms(RXRA1 and RXRA2).
Formulation
Sterile filtered liquid in 20 mM Tris-HCl, pH 7.5 + 0.1 M NaCl + 5 mM b-mercaptoethanol
Storage and Stability
Stable for 4 weeks at 2-4C or in working aliquots at -20C for longer storage. Add a carrier protein (0.1% HSA or BSA) as a stabilizer for long term storage. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Source
E. coli
Molecular Weight
13.6 kDa
Purity
> 95% as determined by RP-HPLC and SDS-PAGE analyses
Endotoxin Level
< 0.1 ng/ug of RXRA

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Menge: 50 ug
Lieferbar: In stock
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