ArtNr |
CS-CRI501A |
Hersteller |
Cell Sciences
|
Menge |
10 ug |
Kategorie |
|
Typ |
Proteins |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
E.coli |
Purity |
98% determined by: HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm |
Sequence |
GPETLCGAEL VDALQFVCGP RGFYFNKPTG YGSSIRRAPQ TGIVDECCFR SCDLRRLEMY CAPLKPTKAA |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
IGF1A, MGF, IGFI, OTTHUMP00000195084, insulin-like growth factor 1, IGF-IA, IGF-IB, somatomedin-C, OTTHUMP00000195082, mechano growth factor, insulin-like growth factor IA, insulin-like growth factor IB |
Lieferbar |
|
Manufacturer - Category |
Biomolecules |
Storage Conditions |
Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage. |
Molecular Weight |
7.6 kDa. |
Description |
Insulin-like Growth Factor I, IGF-I, is a growth factor produced in response to growth hormone-stimulated liver and can be found circulating throughout the body and throughout life. IGF-I activates the IGF-I receptor (IGF1R) and the insulin receptor to mediate growth of almost every cell of the body. IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. Mature human IGF-I is 100% homologous with bovine and pig proteins. Recombinant mouse IGF-I is a non-glycosylated protein, containing 70 amino acids, with a molecular weight of 7.6 kDa. |
Formulation |
Recombinant mouse IGF-1 is lyophilized with no additives. |
Reconstitution |
Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions. |
Specificity |
1 x 106 U/mg |
Biological Activity |
The activity is determined by the dose-dependent proliferation of FDC-P1 cells and is typically less than 20 ng/mL. |
Endotoxin Level |
Measured by kinetic LAL analysis and is typically <= 1 EU/ug protein. |
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