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Recombinant Mouse IGF-1

Recombinant Mouse IGF-1

Manufacturer	Cell Sciences
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite By Cell Type Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Endocrine Regulation of Lipid Metabolism
Type	Proteins
Specific against	Mouse
Amount	10 ug
Host	E.coli
Item no.	CS-CRI501A
Targets	IGF1, INS
eClass 6.1	34160400
eClass 9.0	42020190
Available
Biological Activity	The activity is determined by the dose-dependent proliferation of FDC-P1 cells and is typically less than 20 ng/mL.
Description	Insulin-like Growth Factor I, IGF-I, is a growth factor produced in response to growth hormone-stimulated liver and can be found circulating throughout the body and throughout life. IGF-I activates the IGF-I receptor (IGF1R) and the insulin receptor to mediate growth of almost every cell of the body. IGF-I is known as one of the most potent activators of the AKT signaling pathway which is known to be a stimulator of proliferation and an inhibitor of programmed cell death. Mature human IGF-I is 100% homologous with bovine and pig proteins. Recombinant mouse IGF-I is a non-glycosylated protein, containing 70 amino acids, with a molecular weight of 7.6 kDa.
Endotoxin Level	Measured by kinetic LAL analysis and is typically <= 1 EU/ug protein.
Formulation	Recombinant mouse IGF-1 is lyophilized with no additives.
Molecular Weight	7.6 kDa.
Reconstitution	Centrifuge vial before opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/mL, which can be further diluted into other aqueous solutions.
Storage and Stability	Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein (0.1% HSA or BSA) is added for long term storage.
Specificity	1 x 106 U/mg

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.