EIF3I Antibody

ArtNr	CSB-PA03105A0Rb-50ug
Hersteller	Cusabio
Menge	50 ug
Quantity options	100 ug 20 ug 50 ug
Kategorie	Antibodies Cell Biology Cell Status Apoptosis Western Blot ELISA Immunofluorescence Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, IF, ELISA
Specific against	Human (Homo sapiens), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	eIF-3-beta antibody; eIF3 beta antibody; eIF3 p36 antibody; eIF3-beta antibody; eIF3-p36 antibody; eIF3i antibody; EIF3I_HUMAN antibody; EIF3S2 antibody; EIF3S2; formerly antibody; Eukaryotic translation initiation factor 3 subunit 2 antibody; Eukaryotic translation initiation factor 3 subunit 2 beta antibody; Eukaryotic translation initiation factor 3 subunit I antibody; eukaryotic translation initiation factor 3; subunit 2 (beta; 36kD antibody; eukaryotic translation initiation factor 3; subunit 2 beta; 36kDa antibody; eukaryotic translation initiation factor 3; subunit 2; formerly antibody; eukaryotic translation initiation factor 3; subunit I antibody; Predicted protein of HQ2242 antibody; PRO2242 antibody; TGF beta receptor interacting protein 1 antibody; TGF-beta receptor-interacting protein 1 antibody; TGFbeta receptor interacting protein 1 antibody; TGFbeta receptor-interacting protein 1 antibody; TRIP 1 antibody; TRIP-1 antibody; TRIP1 antibody
Similar products	EIF3I, Eukaryotic translation initiation factor 3 subunit I (eIF3i) (Eukaryotic translation initiation factor 3 subunit 2) (TGF-beta receptor-interacting protein 1) (TRIP-1) (eIF-3-beta) (eIF3 p36), EIF3S2 TRIP1
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Manufacturer - Type	Polyclonal Antibody
Manufacturer - Targets	EIF3I
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	eIF-3-beta antibody; eIF3 beta antibody; eIF3 p36 antibody; eIF3-beta antibody; eIF3-p36 antibody; eIF3i antibody; EIF3I_HUMAN antibody; EIF3S2 antibody; EIF3S2; formerly antibody; Eukaryotic translation initiation factor 3 subunit 2 antibody; Eukaryotic translation initiation factor 3 subunit 2 beta antibody; Eukaryotic translation initiation factor 3 subunit I antibody; eukaryotic translation initiation factor 3; subunit 2 (beta; 36kD antibody; eukaryotic translation initiation factor 3; subunit 2 beta; 36kDa antibody; eukaryotic translation initiation factor 3; subunit 2; formerly antibody; eukaryotic translation initiation factor 3; subunit I antibody; Predicted protein of HQ2242 antibody; PRO2242 antibody; TGF beta receptor interacting protein 1 antibody; TGF-beta receptor-interacting protein 1 antibody; TGFbeta receptor interacting protein 1 antibody; TGFbeta receptor-interacting protein 1 antibody; TRIP 1 antibody; TRIP-1 antibody; TRIP1 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Eukaryotic translation initiation factor 3 subunit I protein (1-323AA)
Dilution	ELISA:1:2000-1:10000 WB:1:2000-1:10000 IF:1:200-1:500
Background	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Epigenetics and Nuclear Signaling
Initial Research Areas	Epigenetics and Nuclear Signaling
Antigen Species	Human
Antigen	Recombinant Human Eukaryotic translation initiation factor 3 subunit I protein (1-323AA)
Clonality	Polyclonal

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Menge: 50 ug

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Lieferung vsl. bis 04.09.2025

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