RAD23A Antibody

RAD23A

hHR 23A antibody; hHR23A antibody; HR23A antibody; MGC111083 antibody; RAD 23a antibody; RAD23 homolog A (S. cerevisiae) antibody; RAD23 homolog A antibody; RAD23 yeast homolog A antibody; RAD23A antibody; RD23A_HUMAN antibody; UV excision repair protein RAD23 antibody; UV excision repair protein RAD23 homolog A antibody

Recombinant Human UV excision repair protein RAD23 homolog A protein (2-201AA)

Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. (Microbial infection) Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome.

>95%, Protein G purified

Epigenetics and Nuclear Signaling

Recombinant Human UV excision repair protein RAD23 homolog A protein (2-201AA)